
The Unbridled Power of Postbiotics
The TruEquine™ postbiotic horse feed additive* line represents Diamond V’s fermentate technology for all ages and levels of horses, from your equine Olympic athlete to your senior horses. TruEquine postbiotic’s dual-action functionality helps support both immune function and digestive health for optimal health and performance.
Research shows Diamond V® TruEquine postbiotic helps support and promote:
TruEquine postbiotic horse feed additive works naturally* with the biology of the horse to help support a healthy immune system, sustaining more stress-free days and supporting joint health and mobility. It also supports a healthy hindgut microbiome for optimal digestion and gut function, soothing the horse’s stomach.
Diamond V continues to build on nearly 80 years of leadership in the research, development, and manufacturing of microbial fermentation technology, creating unique, natural immune health postbiotics. TruEquine postbiotic is manufactured in the United States in our state-of-the-art facilities that meet current Good Manufacturing Practices and other stringent quality criteria.
THE PROOF IS IN THE SCIENCE
TruEquine Postbiotic works with the biology of the animal to maintain immune strength and promote digestive health. No matter their class, type, or life stage, TruEquine supports optimal digestive function in all horses, and can lead to proper stress management, gut health, and joint support.

Prostaglandin E2 (PGE2) is a biomarker often used to assess inflammation. PGE2 can be used as an indicator to evaluate efficient and appropriate response to exercise stress in joint tissue.
TruEquine helped improve joint health following an acute stressor by reducing a joint inflammation marker.
At the six-hour post challenge, TruEquine-supplemented horses demonstrated significantly lower synovial PGE2 indicative of a lower inflammatory marker response.
Overall PGE2 levels were lower in horses fed TruEquine Postbiotic compared to control horses.

Beneficial microbes break down both fiber and undigested starch into useful byproducts called Volatile Fatty Acids (VFAs). These VFAs are then absorbed by the horse as useful energy which can help their gut become healthier, more absorptive, and resilient.
VFAs provide at least 30% of the energy needed by the horse, while also helping maintain the health of the cecum and colon by supporting cell growth, blood flow, and the normal functions of the intestine.
TruEquine contains fermentable nutrients that increase VFA production to help support normal, healthy gut function.
In horses fed TruEquine, VFA concentration was greater compared to control horses or those fed Inulin.

Cortisol is the horse’s main stress hormone that helps manage the body’s response to stress. Research shows that horses fed TruEquine:
- Experience reduced excessive whole-body stress following exercise.
- Respond appropriately to exercise, while experiencing minimized excessive stress afterwards for faster recovery.
- Have more managed and appropriate whole-body response to the stress of exercise.
- Exhibit lower serum concentrations of cortisol compared to control horses.
- Experienc cortisol returning to pre-exercise levels at the one-hour timepoint, while control horses took until the six-hour mark.
- At the six-hour post-exercise timepoint, horses fed TruEquine exhibit 68% lower levels of serum cortisol compared to pre-exercise levels.
FREQUENTLY ASKED QUESTIONS

TruEquine is a natural* immune health postbiotic used in all classes of equine diets to support optimal health and performance.
Research shows TruEquine postbiotic helps support and promote:
- Joint Support
- Gut Health
- Immune Support
Research shows TruEquine postbiotic has dual-action functionality to support immune function and digestive health. TruEquine fermentate helps support your horse’s immune system to maintain immune strength, support digestive tissue integrity, and promote a healthy microbial balance.
The TruEquine postbiotic product line is not a single compound, but rather a microbial fermentate composed of hundreds of bioactive compounds. These bioactives work synergistically with the biology of the animal to support health and performance.
TruEquine postbiotic is produced using Diamond V’s Saccharomyces cerevisiae fermentation technology platform.
View our TruEquine Product Line
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